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SoftWave Therapy 101: The Science Behind Pain Relief, Recovery, and Regeneration with Dr Kale Matovich

Published March 20th, 2025 by Natural Way Chiropractic

If you're searching for long-term pain relief and true healing—without the risks of surgery, injections, or lifelong medication—SoftWave Tissue Regeneration Technology offers a game-changing solution backed by real science and trusted by elite medical institutions and sports professionals around the world.

At Natural Way Chiropractic, Dr. Kale Matovich brings this advanced regenerative technology to Calgary, helping patients optimize recovery, control inflammation, improve mobility, and repair damaged joints, tissues, and nerves—at the source.


What Is SoftWave Therapy?

SoftWave Therapy is a non-invasive, drug-free, and surgery-free regenerative treatment that uses electrohydraulic supersonic acoustic waves, delivered via a broad focused energy shockwave, to initiate a powerful healing response in the body. These waves penetrate deep into tissues, stimulating a cascade of biological processes that repair, regenerate, and restore function—without downtime.

This treatment is used globally for musculoskeletal pain, sports injuries, joint degeneration, soft tissue damage, nerve pain, and more.


SoftWave Healing: Cellular, Joint, and Tissue-Level Science

The therapeutic power of SoftWave lies in its ability to activate the body’s own healing mechanisms—working at the cellular, vascular, and tissue levels simultaneously.

1. VEGF – Vascular Endothelial Growth Factor

SoftWave Therapy stimulates the release of VEGF, a critical protein that promotes angiogenesis (formation of new blood vessels). This process:

  • Enhances oxygen and nutrient delivery to injured areas

  • Accelerates removal of waste and metabolic byproducts

  • Supports healing in poorly vascularized tissues like tendons, cartilage, and ligaments

2. eNOS – Endothelial Nitric Oxide Synthase

The therapy also triggers the upregulation of eNOS, leading to increased production of nitric oxide, a vital signaling molecule that:

  • Relaxes blood vessels to improve circulation

  • Reduces oxidative stress and promotes vascular repair

  • Supports the delivery of immune and growth factors

3. Neoangiogenesis

SoftWave initiates neoangiogenesis, the creation of new microvascular networks. This is essential in chronic degenerative conditions where poor circulation hinders tissue repair. Enhanced blood flow reinvigorates cellular metabolism, promotes detoxification, and accelerates recovery.

4. PCNA – Proliferating Cell Nuclear Antigen

PCNA is a cellular marker involved in DNA replication and repair. SoftWave increases PCNA expression to:

  • Stimulate cellular regeneration

  • Promote tissue growth and renewal

  • Repair damaged tendons, ligaments, muscles, and joints at the DNA level

5. Stem Cell Activation and Migration

One of SoftWave’s most unique effects is its ability to stimulate, activate, and guide resident stem cells to areas of damage. These cells play a vital role in:

  • Replacing damaged tissue with new, functional cells

  • Promoting collagen production and extracellular matrix repair

  • Supporting long-term structural regeneration

6. Flushing Out Senescent Cells

Senescent cells are damaged or aging cells that linger in the body, contributing to chronic inflammation and tissue dysfunction. SoftWave helps to:

  • Clear out senescent cells

  • Make space for new, healthy cellular growth

  • Reduce systemic inflammation and restore tissue health

7. Modulation of Inflammation and Toll-Like Receptors

SoftWave modulates the immune response through toll-like receptors (TLRs), which are responsible for detecting injury and initiating inflammation. By rebalancing these signals, SoftWave:

  • Calms overactive inflammation

  • Supports a controlled and productive healing response

  • Helps resolve chronic pain driven by unresolved inflammation


Trusted by Leading Medical Institutions and Elite Athletes

SoftWave Therapy is not just gaining traction—it’s becoming a recognized standard of care in elite health systems and sports performance settings worldwide.

SoftWave is trusted and used by:

  • The Cleveland Clinic

  • Walter Reed Military Medical Center

  • Mayo Clinic

  • Harvard Medical School

  • Stanford University

  • Piedmont Hospital

  • UCLA Health

  • And many more

In addition, SoftWave is being used by athletes and trainers in:

  • NFL, NBA, NHL, WNBA, MLB, PGA, LIV Golf

  • UFC, MLS, and Premier League soccer

  • NCAA athletic programs

  • Olympic teams and professional sports organizations globally

This is the same technology used by the world’s top medical and sports performance experts, now available locally at Natural Way Chiropractic in Calgary.


The Benefits of SoftWave Therapy

Patients at Dr. Kale Matovich’s clinic are experiencing dramatic improvements in:

  • Pain relief

  • Inflammation reduction

  • Mobility and flexibility

  • Strength and function

  • Tissue and nerve regeneration

  • Post-surgical and sports injury recovery

Whether you’re recovering from an injury, struggling with chronic joint pain, or looking to restore long-term function, SoftWave Therapy is your body’s best chance at natural healing—supported by science, backed by results.


Schedule Your SoftWave Consultation Today!

If you're ready to experience what cutting-edge regenerative medicine can do for your health, don’t wait.

Request a SoftWave Therapy new patient visit online today
Or call (403) 246-0334 to schedule your consultation with Dr. Kale Matovich and the team at Natural Way Chiropractic.


Contact Information

Natural Way Chiropractic
Dr. Kale Matovich, DC
3527 18 Street SW #201
Calgary, AB T2T 4T9
Phone: (403) 246-0334
Email: Info@naturalwaychiro.ca
Learn More About Us On Our Main Website: https://naturalwaychiro.ca
Request a SoftWave Therapy Discovery Session Online Here: https://www.softwavecalgary.com/contact


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